FDA approves novel treatment for hardest depression cases

Source: Carolyn Y. Johnson & Laurie McGinley, Washington Post (Paid Registration)

The Food and Drug Administration approved a novel antidepressantlate Tuesday for people with depression that does not respond to other treatments—the first in decades to work in a completely new way in the brain.

The drug, a nasal spray called esketamine, has been eagerly anticipated by psychiatrists and patient groups as a powerful new tool to fight intractable depression. The medicine has a complex legacy because it is a component of ketamine, which was approved years ago as an anesthetic and was once popular as a party drug called Special K. 

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